Ranking the best blood thinners for 2022

Thickening of the blood can be the beginning of such serious diseases as varicose veins, thrombosis, thrombophlebitis, atherosclerosis, heart attack, stroke, and other malfunctions of the cardiovascular system. The editors of top.htgetrid.com/en/ bring you a ranking of the best blood thinners that will help prevent a number of diseases. The review included medicines that received the highest customer rating. When selecting drugs, special attention was paid to the effectiveness of drugs, their cost, safety and ease of use.

The best means for thinning the blood of the antiplatelet group

The action of antiplatelet agents is aimed at preventing platelets from sticking together. Medicines of this group are used in the treatment of such cardiological diseases as the consequences of ischemic stroke, angina pectoris, peripheral arterial disease, the prevention of infarction and the treatment of its consequences, as well as in bypass and stenosis of the coronary arteries.

Deplatte

The action of this drug is aimed at the prevention of peripheral arterial occlusion, ischemic stroke, atrial fibrillation, myocardial infarction. Deplatt's active ingredient is clopidogrel. In medical practice, its combination with acetylsalicylic acid is often used. The interaction of these two substances is used to prevent thrombotic complications in the acute form of the coronary syndrome. Deplatt is available in the form of tablets, the dosage of which is 75 mg. The following scheme of application is usually prescribed: 1 tablet per day, regardless of the meal. The average cost of this drug is 439 rubles.

• Excellent connection with blood plasma proteins - 98-94%;
• Ease of use;
• The time of maximum concentration is only 45 minutes;
• Acceptable cost.

• The minimum age of application is 18 years.

Cardiomagnyl

Cardiomagnyl is a compound of two substances - acetylsalicylic acid and magnesium hydroxide. The mechanism of action of aspirin is aimed at blocking the synthesis of thromboxone and suppression of platelet aggregation. Magnesium hydroxide prevents the aggressive effects of acetylsalicylic acid on the mucous membranes of the digestive system.

This drug is used as protection against re-infarction, for the prevention of cardiovascular diseases, thrombosis and thromboembolism, as well as unstable angina. Cardiomagnyl has several forms of release: 20 and 100 tablets. On average, the cost of this remedy is 116 rubles for 30 tablets. It is released without a prescription.

• Affordable price;
• Few contraindications;
• Prevalence;
• Efficiency.

• The frequency of side effects.

Egitromb

Egitromb is used to prevent complications in ischemic stroke, arterial occlusive disease, myocardial infarction, acute coronary syndrome, atrial fibrillation, unstable angina. The active ingredient in this drug is clopidogrel hydrosulfate. The advantage of Egitromb is an excellent connection with plasma proteins, which is 94-98%.

Inhibition of platelet association occurs within 2 hours after the use of this drug. The maximum efficiency is shown in 4-7 days. This antiplatelet agent is available as film-coated tablets. Their dosage is 75 mg. Release form - 14 and 28 pcs. packaged. The duration of therapy depends on the severity of the disease. The minimum period is a few days, the maximum is six months. 75% of the drug is excreted through the intestines, 46% through the kidneys. The average price of Egitromb is 883 rubles per package with 28 tablets.

• High bioavailability;
• Convenient regimen - 1 tablet per day;
• A small number of contraindications;
• Great efficiency.

• High price;
• Not to be used by children under 18 years of age.

Curantyl

Curantyl is available in packs of 40 (75 mg), 100 (25 mg) and 120 (25 mg) tablets.The active ingredient in this remedy is dipyridamole. It has a wide range of effects on the body. The drug does an excellent job of improving placental and venous outflow, lowering blood pressure, dilating blood vessels, normalizing the rheological properties of blood, reducing the resistance of cerebral vessels (especially important for people over 40 years old). In addition, Curantil has proven itself as an immunomodulator.

For the prevention of respiratory diseases and influenza, 50 mg of the substance is prescribed once a week for 4 weeks. For the prevention of other diseases, the dose is increased to 75-600 mg per day, depending on the severity of the case. Tablets should be taken in the morning on an empty stomach with a small amount of liquid. On average, the price for a pack of 120 tablets is 590 rubles.

• Acceptable cost;
• Extensive scope;
• Suitable for lactating and pregnant women;
• The minimum number of contraindications;
• Convenient release form.

• Not detected.

Trental

The main active substance of Trental is pentoxifylline. Its advantage is the ability to thin the blood in 2 ways. In addition to reducing platelet adhesion, the substance also affects red blood cells, improving their ability to tolerate deformation. Also, the use of this drug helps to reduce the concentration of fibrinogen, the activity and adhesion of leukocytes.

Trental is used for poor blood circulation in the vascular and retina of the eyes, cerebral circulation disorders, degenerative changes, diabetic genesis, otosclerosis, occlusive disease and trophic disorders.It is also often used to treat chronic peripheral circulatory disorders in the elderly. Packages are available in 400 (400 mg), 60 (100 mg) and 20 (400 mg) tablets. You can also purchase a concentrate for self-preparation of the solution. The average price of Trental is 496 rubles for 60 tablets.

• Good price;
• High bioavailability;
• Convenient release form;
• The optimum ratio of price and quality;
• Complex action.

• Lots of contraindications.

Acetylsalicylic acid

Acetylsalicylic acid is a budget over-the-counter antiplatelet agent that is highly effective not only in the prevention of blood clots. This substance is used to treat inflammation, reduce fever and reduce pain. Often used for fever, Kawasaki disease, arthritis, pericarditis, headache, varicose veins, cardiovascular disease. Also, this medication has shown itself well in the prevention of heart attacks and strokes.

This drug is supplied in packs of 10, 20, 30 and 40 tablets, where the amount of active ingredient is 500 mg. There are also packs of 30 and 20 tablets with quantities of 100 and 300 mg. The dosage of aspirin depends on the type of disease. The minimum amount of a substance per dose is 0.1 g, the maximum is 3 g. On average, the cost for 20 tablets is 15 rubles.

Acetylsalicylic acid is included in the list of important medicines of the Russian Federation and the World Health Organization.

• Low price;
• Proven safety;
• Wide range of therapeutic actions;
• Quick result;
• Lots of positive feedback.

• A large number of contraindications.

The best blood thinners of the anticoagulant group

Anticoagulants prevent the formation of blood clots by affecting proteins in the blood. These funds are used in cardiology practice in the treatment of heart failure, cardiac arrhythmias, infective endocarditis, mitral valve stenosis, thromboembolism, prosthetic heart valves and thrombosis.

Fraxiparine

The active substance of Fraxiparine is nadroparin calcium, obtained by depolymerization from conventional heparin. The low molecular weight substance is highly effective in preventing the formation of blood clots and inhibiting the activity of the blood coagulation system. This is possible due to its high ability to bind to plasma protein. The advantage of this substance is its almost complete bioavailability - about 98% and the minimum absorption time - 3-5 hours.

This drug shows excellent results in the prevention and treatment of myocardial infarction, unstable angina, thromboembolism, blood clotting during hemodialysis. Fraxiparine is supplied as a solution for injection. There are several forms of release: ampoules of 0.3, 0.4, 0.6 and 0.8 and 1 ml. The average price of this medicine is 2,540 rubles for 10 syringes of 0.3 ml.

Note! The use of Fraxiparine implies constant monitoring of the platelet count, as there is a high probability of developing heparin-induced thrombocytopenia.

• High efficiency;
• Excellent bioavailability;
• Several forms of release.

• High price.

warfarin

Warfarin was registered in 1948 but was originally used as a rodent poison.As a therapeutic anticoagulant, the drug began to be used in 1954, after a series of studies. The drug is available in tablets that contain 2.5 mg of the active substance - warfarin sodium. The minimum number of tablets in a package is 30 pieces, the maximum is 150 pieces. Warfarin is available by prescription.

The mechanism of action of this medication is aimed at suppressing the synthesis of proteins S, C and vitamin K-dependent blood coagulation factors in the liver. The rheological properties of blood improve after 3-5 days of use. It is necessary to take Warfarin 1 time per day and at the same time. The initial dose is one to two tablets. Depending on the severity of the disease, the dose may be increased. The drug is excreted by the kidneys. Average cost: 88 rubles per 100 tablets.

• Affordable price;
• Low likelihood of side effects;
• Ease of use;
• Availability in any pharmacy;
• High efficiency.

• Many contraindications;
• Incompatibility with a large number of medicines.

Pradaxa

Pradaxa is a new generation prescription drug that does not have pharmacological activity, but belongs to small molecular weight prodrugs. Its active ingredient, dabigatran etexilate, has an anticoagulant effect within 2-3 hours after ingestion. The prodrug is excreted through the gastrointestinal tract (6%) and kidneys (85%).

Pradaxa is available in the form of oblong, hard capsules, the amount of the substance of which is 75, 110 or 150 mg. Dosage regimen - 2-3 times a day, 1-2 capsules.This anticoagulant is on the list of essential medicines of the World Health Organization, which confirms its effectiveness and safety. The average cost of Pradax is 1,762 rubles, for 30 capsules with a dosage of 75 mg.

A prodrug is a chemically modified form of a drug or compound that is converted into a pharmacologically active drug directly in the human body.

• High bioavailability;
• Rapid absorption;
• No need for regular blood tests;
• Safe composition;
• Efficiency;
• Few contraindications.

• High price.

Clexane

The active ingredient in Clexane is enoxaparin sodium. The drug is available in the form of a solution. For ease of use, the solution is placed in disposable syringes with a volume of 0.2, 0.4, 0.6, 0.8, 1 ml. Its advantage is almost 100% bioavailability, since the solution is injected directly under the skin, in the shoulder or abdomen. The maximum activity of the drug in the blood plasma is observed after 3-4 hours. Removal of Clexane is carried out by the kidneys.

This anticoagulant is used for the prevention and treatment of venous thrombosis and embolism, and is also often used in the acute form of a heart attack. The medicine is prescription, it is recommended to use in the conditions of inpatient treatment. If it is necessary to administer the solution at home, a step-by-step instruction is included in the package. Usually the course of admission is from 3 to 7 days. On average, the cost of a medication is 607 rubles for a volume of 0.6 ml.

• performance;
• Excellent bioavailability;
• Therapy of angina pectoris and acute myocardial infarction;
• Minimum side effects;
• Few contraindications.

• Very high price;
• One release form.

Plavix

Plavix is ​​another representative of prodrugs. Its active ingredient is clopidogrel hydrosulfate. The drug is very popular in the treatment of consequences after attacks of stroke and myocardial infarction. Also successfully used in acute coronary syndrome and atherosclerosis.

Plavix is ​​available in packs of 10, 28 and 100 tablets, the dosage of the active ingredient in 1 tablet is 75 or 100 mg. The scheme of application is simple: 75 mg 1 time per day. The effect of the drug occurs 2 hours after its administration. The drug is excreted through the intestines (46%) and through the kidneys (50%). The average cost of a package is 3,010 rubles (100 tablets, 75 mg)

• High efficiency;
• Several forms of release;
• Complex action;
• Application does not depend on the time of the meal.

• High price.

Wessel

Wessel's advantage is naturalness. Its active component, sulodexide, is a compound of a heparin-like fraction (80%) and dermatan sulfate - 20%. Dermatan sulfate is isolated from the mucous membrane of the porcine intestine. The medicine is suitable for thinning the blood and strengthening the walls of blood vessels. It is also used for dyscirculatory encephalopathy, acute ischemic stroke, peripheral arterial lesions, microangiopathy.

The dosage form of this remedy is a light yellow solution in ampoules or capsules. Usually the treatment is prescribed as follows: intramuscular or intravenous administration of the solution 1 time per day for 15-20 days, then taking 1-2 capsules per day for 30-40 days. Wessel acts within 15 minutes after application.The drug is excreted by the kidneys. On average, the cost of the drug is 2,747 rubles.

• Versatility;
• Possibility of use during pregnancy;
• Good tolerance;
• Not addictive;
• High efficiency;
• Safe composition.

• Expensive.

Where can you buy the drugs listed in the rating?

All the products presented in this review can be ordered online at online pharmacies or at offline pharmaceutical outlets.

Conclusion

The review presented the best, most effective and safest blood thinners, which were selected based on positive consumer feedback. Before buying any of the presented funds, it is necessary to consult a specialist!