Ranking of the best proton pump inhibitors for 2022

Diseases of the digestive system require treatment. With an increase in the level of hydrochloric acid in the stomach, specialists prescribe drugs that maintain the required level of the substance and reduce discomfort. The rating of the best proton pump inhibitors for 2022 will help determine the choice of the most effective drugs, according to experts.

What are proton pump inhibitors

Proton pump inhibitors (PPIs) are drugs that reduce the secretion of hydrochloric acid. The substance penetrates the cell and blocks the process of acid production for a certain time. Medicines are prescribed by doctors, after studying the cause, which provoked a large amount of hydrochloric acid in the digestive organs.

Who is prescribed PPI

PPI preparations can be prescribed both for diseases of the digestive system and for prevention. Most often, all medications are prescribed:

• with a disease of the stomach or duodenum;
• to fight the Helicobacter bacterium: if this bacterium is detected in a person, the acid level may be normal, but inhibitors are recommended for preventive purposes;
• malignant tumors that block the normal passage of food from the stomach to the esophagus;
• disorders of the pancreas;
• with a long course of treatment with anti-inflammatory substances, which can be negatively displayed on the gastric mucosa.

PPIs are often used in complex therapy. Facilitate the effect of drugs on the digestive organs and relieve unpleasant symptoms.

Varieties of PPI

All proton pump inhibitors are divided into the following types:

• first generation;
• second generation;
• third generation;
• fourth generation;
• fifth generation.

When choosing the most suitable remedy for a person, the disease and accompanying symptoms are taken into account.

Overview of the Best Proton Pump Inhibitors

Among the wide variety of medicinal substances, it is necessary to highlight the most effective for 2022.

First generation

Nolpaza

The drug belongs to the first generation and is often prescribed for stomach ulcers and diseases of the duodenum. The agent is often prescribed in complex therapy and reduces the consequences after prolonged use of anti-inflammatory drugs.

The active substance is quickly absorbed into the cells and reduces the amount of hydrochloric acid, thereby reducing discomfort in the digestive organs. The substance is suitable for long-term treatment and is excreted by the kidneys.

The drug can be used prophylactically for patients who are at risk of exacerbation of peptic ulcers. The drug has a convenient form for use and affordable cost. The tool is not contraindicated when driving.

• long-term result;
• can be used while driving a vehicle;
• There are packs of different sizes.

• allergic reactions are possible.

Cost: from 200 rubles.

Omeprazole

The drug is very popular and is often used for diseases of the digestive system. It has the form of capsules with granules. The enteric coating disintegrates after consumption and the granules penetrate the cells blocking the release of hydrochloric acid.

The agent is quickly absorbed, and the desired result is achieved in a short time. It is prescribed for acute diseases, as well as during the period of drug therapy. It is recommended to use the substance during meals. However, it should be noted that the drug is not suitable for people with renal or hepatic insufficiency. It is also not recommended to take Omeprazole to the elderly and during the period of bearing a child.

• quick effect;
• not many side effects;
• can be used for prevention.

• not suitable for the elderly.

The cost is 100 rubles.

Omez

An affordable drug that can be found in almost every medicine cabinet. A feature of the tool is a quick effect. Available in the form of capsules. For people who find it difficult to swallow the capsule, you can open it and mix the contents with water. The substance dissolves well.

It is excreted mainly by the kidneys, so patients with renal insufficiency should first consult with a specialist.

It should also be noted that the substance can be administered during pregnancy. However, the dosage is minimal and strictly under the supervision of the attending physician.

• affordable cost;
• the effect is achieved quickly;
• suitable for long term treatment.

• reception has side effects such as headache and nausea.

The cost is 100 rubles.

Ortanol

Another drug that is often prescribed for the treatment of diseases of the digestive system. The medicinal substance has an affordable cost and high efficiency. You can buy the drug without a doctor's prescription. It is used to eliminate pain, it can also be prescribed for heartburn and bloating.

In order to avoid side effects, it is necessary to consult with your doctor before use. Not recommended for use during pregnancy and lactation. Also, the substance should be used with caution for people in old age.

• affordable cost;
• high efficiency;
• can be purchased without a prescription.

• not found.

The cost is 150 rubles.

Second generation

Lancid

Medicinal product of accumulative action.The desired result is achieved 4 days after application. The product is available in the form of capsules, which quickly dissolve under the action of gastric juice.

Experts recommend using the medication an hour before meals. Since products can reduce the intensity of penetration into the walls of the stomach. After the end of therapy, the drug is excreted after 4 days.

The medication is acceptable for use during pregnancy, but under the supervision of the attending physician. The medicinal substance may cause side effects such as bloating and headache.

• long-term action;
• convenient form;
• high efficiency.

• possible side effects.

The price is from 350 rubles.

Lansoprol

An antiulcer is often prescribed to block stomach acid, regardless of the cause. After use, the medicinal substance is rapidly absorbed and penetrates into the lesion. To achieve the desired result, the tablets are recommended to be used 2 times a day one hour before meals. However, the dosage can be selected individually depending on the complexity of the disease.

The drug is not recommended for use in patients with renal insufficiency. Treatment with a substance during the period of bearing a child is also prohibited. Also, experts do not recommend the use of tablets for patients who use theophylline.

• not addictive;
• easily digestible;
• has a lasting effect.

• many side effects.

The cost is from 200 rubles.

third generation

Controloc

The drug can only be purchased with a prescription from your doctor.It is based on the active substance pantoprazole, due to which relief comes quickly and unpleasant symptoms decrease.

The drug is suitable for long-term treatment. Excreted from the body with urine and rarely causes side effects. Suitable for people with kidney failure and the elderly. However, it is not recommended for use on persons under 18 years of age, as the end result has not been studied.

• tablets are small, easy to use;
• few contraindications;
• affordable cost.

• not detected.

The cost is 150 rubles.

Epicurus

The medicinal substance is very popular, as it allows you to quickly reduce discomfort and has a small number of negative consequences. Suitable for the treatment of diseases even in the last stages of development. After consumption, it quickly penetrates the cells and blocks the release of hydrochloric acid.

Available in the form of convenient capsules with small granules. After dissolution of the shell, the granules spread through the stomach and duodenum. Often the drug is prescribed for the treatment of peptic ulcers.

The drug is not suitable for pregnant women and children. It should also be used with caution in the elderly and in patients with renal insufficiency.

• improves the process of digestion;
• quickly absorbed;
• has a cumulative effect.

• has contraindications.

The price is from 500 rubles.

fourth generation

Pariet

The drug is based on the substance rabeprazole. It is used most often in advanced stages of diseases of the digestive system. After use, the desired result is achieved after 1 hour. Suitable for long-term treatment, rarely causes side effects.

Despite the fact that the medicine has a rather high cost, user reviews about it are mostly positive. With regular use, the substance is not addictive, and is suitable for people with kidney failure

• long-term result, persists even after the end of therapy;
• produced in several forms;
• well combined with other drugs.

• high price.

The price is from 1500 rubles.

Razo

The drug after use within 30 minutes begins to act. Therefore, discomfort and unpleasant symptoms quickly pass. The achieved result is stored during the day. Tablets are small, so it is easy to use even on the road. In order to normalize the release of hydrochloric acid, it is enough to take one tablet per day.

Often the drug is prescribed in complex therapy in the treatment of not only the digestive system, but also other diseases. The package contains 30 tablets, so it lasts for a long period.

• quickly begins to act;
• small sizes;
• few side effects.

• not recommended for use during pregnancy.

The cost is 300 rubles.

Fifth generation

Nexium

The drug belongs to the latest generation and is highly effective. As part of esomeprazole, which quickly penetrates into the lesion and blocks the process of acid production. Thanks to this action, heartburn, stomach pain and heaviness are reduced.

The drug is often prescribed by specialists not only during the treatment of diseases of the digestive system, but also in complex drug therapy. A feature of the remedy is that it can be used even with renal failure.However, experts recommend individually select the dosage. Also, the drug can be prescribed for patients in old age.

• high efficiency;
• quickly absorbed into the walls of the stomach;
• does not cause an overdose, subject to the recommendations of a specialist;
• long lasting result.

• not detected.

The cost is from 700 rubles.

Emanera

A drug that has appeared relatively recently. According to users, the substance quickly reduces discomfort and practically does not cause side effects. The active ingredient esomeprazole quickly penetrates the walls of the stomach and reduces the amount of acid. As a result, digestion is normalized and heaviness and pain are reduced.

It can be prescribed for almost all disorders of the digestive system. The manufacturer produces two dosages, so choosing the right variety is not difficult.

The drug is produced in the form of capsules that are easy to swallow. A special quick-dissolving shell allows you to achieve the desired result immediately after use.

• a large number of positive reviews;
• fast result, which lasts for a day;
• convenient capsules.

• not found.

The cost is 300 rubles.

Dexilant

The newest drug, which is gaining great popularity among users. A feature of the drug is that after use the capsule is not completely dissolved. The drug dissolves gradually, so that a positive result is maintained for a long period.

The tool has practically no side effects. In rare cases, bloating, flatulence, and nausea may occur.The drug is not prescribed for pregnant women and under 18 years of age and for people with allergic reactions.

• long-term action;
• simple use.

• not detected.

The cost is from 700 rubles.

What you need to know about PPI

Medicines must be prescribed by doctors. Using the API, you need to know the following information:

• with long-term treatment, PPIs can change the pH of the stomach, so it is necessary to monitor changes and stop therapy in a timely manner;
• often there are erroneous opinions that drugs increase the effectiveness of antibiotics, experts note that PPIs contribute to the development of the necessary environment for the rapid action of drugs;
• while taking PPIs, it is forbidden to use acidic foods, such foods can increase acidity and block the effect of the medicinal substance;
• it is not recommended to use several PPIs at the same time, such therapy can lead to an overdose or lack of the desired result.

Before using the drugs, you must carefully read the instructions. Of particular importance should be paid attention to side effects and possible contraindications.

Outcome

Proton pump inhibitors are necessary in order to restore the functioning of the digestive organs and reduce the amount of hydrochloric acid. Properly selected drugs do not cause side effects and can be used for long-term treatment. When choosing a suitable product, you must carefully read the instructions and consult with your doctor. The ranking of the best proton pump inhibitors for 2022 describes all the popular drugs that have repeatedly earned positive user reviews.