Rating of the best analogues of Acyclovir for 2022

The category of drugs with antiviral action includes Acyclovir, which can suppress various types of herpes infection. For immunocompromised patients, this is especially important. In many cases, it becomes an ideal assistant in the fight against warts and herpes on the lips. In addition, the medicinal properties make it possible to steadfastly resist chickenpox, lichen, cytomegalovirus, and many other ailments.

General information

Analogues - drugs containing various active elements with the same purpose for use in the same diseases.

At the same time, their indications, contraindications and doses differ, as well as the therapeutic effect on the body. They are not an equivalent replacement and the intake is carried out under the supervision of a pharmacist or doctor.

Types and forms

Substitutes do not have to be exactly the same as the originals. Their main purpose is to continue the course of treatment without significant adjustment. At the same time, preclinical and clinical trials are carried out with replacement drugs to confirm safety and efficacy.

Original brands are subject to mandatory registration.

After the expiration of a patent for a medicinal formula, it becomes publicly available to other manufacturers and it becomes possible to produce analogues. Copies are as follows:

1. Generics are low-cost, low-cost drugs with a high production rate. They can be ordered online or bought at a pharmacy.
2. Brand analogues - are manufactured under a trademark and have a unique name.

Orders:

• with identical active substance, dosage and form of release;
• with the same active substance and dosage, but different form;
• with the same active ingredient, but different dosage and form;
• with a selected ATC classification, but differences in the active substance, dosage and form. The clinical effect corresponds to the original.

The domestic market is filled with various antiviral drugs, incl. Acyclovir and its analogues, from the best manufacturers. Basic forms:

• tablets;
• capsules;
• creams for external use;
• eye ointments;
• powders;
• drops;
• solutions for injections.

Patients are advised to have regular blood and urine tests at the time of treatment to monitor liver and kidney function. In the case of intravenous use, neurotoxicity may occur with the appearance of agitation, changes in consciousness, confusion of thoughts. With a large overdose, renal failure may occur.

Indications and contraindications

Acyclovir and its analogues provide assistance in the following cases:

1. Treatment of mucous membranes and skin infections.
2. Complex therapy for immunodeficiency or in the postoperative period after bone marrow transplantation.
3. Prevention of relapses and exacerbations as a result of infectious diseases.
4. Skin lesions or stomatitis caused by herpes.
5. Angina, SARS, respiratory diseases.
6. Chicken pox, ulcers.
7. Eye infections.

Application is contraindicated in:

• hypersensitivity;
• lactation;
• less than three years of age;
• lactase deficiency.

It should be used with caution during childbearing, with dehydration, hypoxia, renal pathologies, neurological disorders, electrolyte imbalance.

Video about acyclovir:

Side effects

The use of analogues can cause negative manifestations:

• hematopoietic system: anemia, thrombocytopenia or leukopenia;
• gastrointestinal tract: diarrhea, abdominal cramps, nausea;
• central nervous system: agitation, ataxia, dizziness, weakness, hallucinations, dysarthria, fatigue, paresthesia, drowsiness, confusion, tremor;
• respiratory organs: shortness of breath;
• urinary system: renal colic or insufficiency, increased urea and creatinine;
• allergic reactions: anaphylaxis, angioedema, itching, rash, syndromes (Stevens-Johnson, Lyell);
• others: alopecia, lymphadenopathy, fever, weakness, fever, blurred vision, edema;
• intravenous administration: inflammation, necrosis (in case of subcutaneous spread);
• external use: soreness;
• in the eye area: burning, conjunctivitis, keratopathy.

However, not all patients experience problems. In the event of the first signs of malaise, you must immediately inform your doctor or pharmacist. While taking the medicine, you should drink plenty of fluids. The attending physician should be informed about pregnancy and lactation.

Special care should be taken with dosages in the elderly, patients with renal insufficiency and pregnant women.

The course of treatment is not independently prescribed, but determined by specialists.

Admission procedure

Aciclovir substitutes are well tolerated and can be used at home. However, due to possible drowsiness or dizziness, you should refrain from driving. Due to the slowing down of the reaction, the most negative consequences are possible.

The drugs are available for oral administration alone or with food. Tablets should be swallowed whole, not chewed or crushed. In a liquid state, it is better to shake the solution before use.

When using an ointment or cream, hands are thoroughly washed before and after application. Avoid contact with eyes. The affected area does not need to be rubbed. It is applied to the skin using gloves to prevent further spread of the infection.

The medicine is stored at room temperature. After the expiration date, the medicine must be disposed of.

Before taking, you should study the instructions in detail.

Criterias of choice

Each person chooses medications differently. Some carefully study the components that make up the drug, others carefully read the characteristics, others prefer products of popular brands, and only the best novelties are suitable for the fourth.

Experts advise to abandon any initiative in this matter, so as not to make mistakes when making an independent choice.

You must follow the recommendations of your doctor.

If Acyclovir is available for sale, it should be purchased. In case of absence, experts advise buying a substitute based on the ratio of quality parameters and price. Medicines are available in various packages and are sold without a prescription.

It is better to choose a complete analogue with an identical composition, including the release form and dosage. In this case, the course of treatment can be continued without changes and any deviations or side effects can be avoided.

It is advisable not to buy medicines with an increased dosage. Possible overdose can cause negative consequences.

The release form doesn't really matter. If a syrup is prescribed, which was not in the pharmacy kiosk, do not give up oral capsules or tablets.

The method of administration indicated by the specialist should not differ. Therefore, it is impossible to replace tablets with injections.

When choosing a combination drug, you should consult your doctor. Indeed, in an individual case, it may be ineffective and harm health.

The brand should be chosen based on the recommendations of doctors and personal preferences. It should be borne in mind that drugs are available for children and adults.

Dosage is important when choosing.Tablets are usually supplied in blisters of five or 10 pieces containing one to five plates per box. Creams and ointments are contained in tubes with a volume of two to five grams. Powders are poured into ampoules of 125, 250 or 500 milligrams. Solutions are poured into bottles of 5, 10 or 20 ml.

 

The best analogues of Acyclovir

The rating of quality drugs is developed on the basis of customer reviews on the pages of online stores. The popularity of models is due to their effectiveness, lack of side effects and price.

The review includes consideration of the best analogues in terms of therapeutic effect and active substance.

TOP-5 best analogues of Acyclovir by action

Panavir

The owner of the registration certificate is OOO National Research Company (Russia).
Producer - CJSC "Green Dubrava" (Russia).

A safe medicinal product based on a plant component with natural antiviral properties. Often used in dentistry in the treatment of herpes infections. As a rule, the appointment is variable, used in complex treatment. It has mixed reviews among doctors and patients due to the lack of an evidence base for effectiveness. In the process of application, immediately after application, a slight itching may occur, which quickly passes.

Price - from 134 rubles.

• active substance based on a plant component;
• safe application;
• positive feedback from patients and doctors;
• affordable price.

• lack of evidence base for effectiveness;
• there are negative user reviews.

Fenistil Pencivir

The owner of the registration certificate is Bittner Pharma LLC (Russia).
Manufacturers - Medgenix Benelux (Belgium), Novartis Pharma Production (Germany).

A popular anti-herpes cream with a long-term therapeutic effect, rarely found in pharmacies. Provides prompt assistance when the first symptoms of the disease appear. Advanced cases require additional intake of antiviral tablets. Patients tolerate the drug well, there are no side effects, there are no discomfort during application.

Price - from 470 rubles.

• good help with herpes;
• long therapeutic effect;
• there are no side effects;
• positive feedback from the medical community.

• difficult to find in pharmacies;
• high price.

Devirs

The owner of the registration certificate is JSC "Vertex" (Russia).
Producer - JSC "Vertex" (Russia).

An effective drug that replaces Acyclovir for the rapid removal of swelling, irritation and itching. It helps well with advanced herpes on the lips without the need to take additional pills. Dosage form in the form of a homogeneous white cream for external use. When applied, there are no unpleasant sensations, there is no specific smell. Contraindicated for use in children and adolescents under 18 years of age. Available in large tubes of 15 and 30 grams.

Price - from 200 rubles.

• rapid impact on the affected areas;
• high efficiency with advanced herpes;
• no specific odor;
• large tube volume.

• overpriced;
• Not intended for patients under the age of 18 years.

Alpizarin

The owner of the registration certificate is JSC Pharmacenter VILAR (Russia).
Producer - JSC Pharmacenter VILAR (Russia).

A universal drug with good immunomodulatory and antiviral properties. Usually prescribed for aphthous stomatitis, chicken pox, herpes, shingles.Patient tolerance is very good. Safety in use allows it to be used in the treatment of children after one year. Side effects in the form of local reactions are rare. To obtain the main active substance, plant components are used. Shelf life without opening the tube up to five years.

Price - 76 rubles.

• immunomodulatory and antiviral action;
• a wide range of applications;
• safe to use;
• allowed for children older than one year;
• available in dosages of 2, 10 and 20 grams;
• excellent value for money.

• hard to find in pharmacies.

Herpferon

The owner of the registration certificate is FIRN M LLC (Russia).
The manufacturer is FIRN M LLC (Russia).

Combined drug of domestic production with simultaneous antiviral action, pain relief and increased local immunity. Gynecologists and dentists are often prescribed as a primary or secondary remedy in the treatment of recurrent herpes, depending on the activity of the rashes.
Cold sores on the lips are reduced in just two to three days. When applied to mucous membranes does not cause irritation.

Price - from 178 rubles.

• high efficiency;
• quick impact;
• contains lidocaine, which relieves pain;
• improves local immunity;
• eliminates recurrent herpes.

• long-term use is not recommended;
• not always available for sale.

comparison table

Brand	Panavir	Fenistil Pencivir	Devirs	Alpizarin	Herpferon
Active substances	sum of polysaccharides of potato shoots	penciclovir	ribavirin	tetrahydroxyglucopyranosylxanthene	lidocaine, acyclovir, interferon alfa
Dosage form	gel 0.002%	cream (with tinting effect) 1%	cream 7.5%	ointment 2%, 5%;	ointment
Aluminum tubes, g	3, 5, 10, 30	2, 5	15, 30	2, 10, 20	5, 10, 30
Expiry date, year	3	3	3	5	2

TOP-5 best analogues of Acyclovir by active substance

Acigerpin

The owner of the registration certificate is Agio Pharmaceuticals Ltd (India).
Manufacturer - Agio Pharmaceuticals Ltd (India).

An Indian antiviral drug that is rarely found in the pharmacy environment and is not very popular in the medical community. There are few reviews on the Internet about the effectiveness of doctors. Available in various packages, incl. in large 10 grams for a full course of treatment. The content of the active substance and the main characteristics correspond to the original medicine. According to patients, it has a quick effect in the treatment of herpes in the early stages of the disease.

Price - from 78 rubles.

• quick treatment of herpes;
• large volume of the tube;
• convenient application;
• reasonable average price.

• difficult to find in the pharmacy network;
• insufficiently qualified reviews.

Vivorax

The owner of the registration certificate is Cadila Pharmaceuticals Ltd (India).
Manufacturer - Cadila Pharmaceuticals Ltd (India).

An Indian drug with antiviral properties that is not widely used in the domestic market and is rarely prescribed by doctors. Available in the form of a cream and tablets for the appointment of diseases of chickenpox, herpes or herpes zoster. It is used for complex treatment in conjunction with drugs taken orally, or monotherapy. In the pharmacy network is not very common because of the affordable price.When applied, side effects may occur - dryness of the mucous membranes or skin at the sites of application, as well as allergic reactions.

Price - from 56 rubles.

• suitable for complex treatment and monotherapy;
• available in the form of tablets and cream;
• budget price.

• some expert opinions;
• hard to find for sale.

Zovirax

The owner of the registration certificate is GlaxoSmithKline Healthcare (Russia).
Producer - Glaxo Wellcome Operations (Great Britain).

A well-known original drug, on the basis of which the Russian analogue was developed. It has various medicinal forms - ointments, creams and tablets. In the medical environment, it is considered the best remedy for the treatment of herpes. Shows quick results when used in the early stages of the disease, effectively relieving burning and itching. In an advanced case, a combined use of an ointment with oral administration of tablets is required. The tolerability of the drug is very good, but the tablets may have mild side effects.

Price - from 163 rubles.

• original medicines;
• high efficiency;
• fast impact
• various assortment of release in the form of ointment, cream and tablets.

• overpriced compared to analogues of Acyclovir.

Herperax

The owner of the registration certificate is Micro Labs Ltd (India).
Manufacturer - Micro Labs Ltd (India).

A budget analogue of a popular drug with highly effective antiviral properties from an Indian manufacturer. It is a white ointment, which after application to the lips is not very noticeable. However, the absorption process is very slow.In the treatment of diseases in the early stages, it has a quick effect and allows you to get rid of herpes in three to four days. Appointment is provided in cases of detection of chicken pox and shingles.

Price - from 48 rubles.

• high efficiency;
• fast action;
• relieves herpes in three to four days;
• available in the form of tablets and ointments;
• Excellent value for money and quality.

• not often on sale in pharmacies;
• some feedback from the medical staff.

Zovirax Duo-Active

The owner of the registration certificate is GlaxoSmithKline Healthcare (Russia).
Producer - Glaxo Wellcome Operations (Great Britain).

A popular combined analogue offered by the manufacturer of the original product, with the addition of hydrocortisone to the active substance to enhance the effect, as well as relieve itching and swelling. Demonstrates pronounced symptomatic properties with rapid relief for patients. In the case of application at the initial stage of herpes, the papules are dried in two to three days. To increase the effectiveness in a neglected state, additional intake of drugs based on Acyclovir may be required. In the medical environment, it is considered one of the most effective means for getting rid of a herpetic rash.

Price - from 335 rubles.

• combined composition;
• high efficiency;
• rapid elimination of symptoms;
• removal of puffiness and itching.

• requires regular application every four hours;
• overcharge.

comparison table

Brand	Acigerpin	Vivorax	Zovirax	Herperax	Zovirax Duo-Active
Active substances	acyclovir	acyclovir	acyclovir	acyclovir	acyclovir, hydrocortisone
Dosage form	cream for external use 5%	cream for external use 5%	cream for external use 5%	ointment for external use 5%	cream for external use
Aluminum tubes, g	5	5	5	5	2
Expiry date, year	3	3	3	3	2

Doctor's advice

1. The scheme of application is developed by the attending physician.
2. Children and adults can take the anti-herpes drug for five days at 200 milligrams daily. For the smallest patients up to two years, the dosage is halved.
3. Creams and ointments are applied to the affected area in a thin layer every four hours.
4. In severe cases and complications, the drug is administered intravenously, depending on the patient's body weight.

Take care of yourself and your loved ones!